Revolutionise the way you develop and produce tablets
| Why lengthy off-line quality controls and rejected batches, if you can monitor quality online and always produce the same end quality, reducing the waste to zero? |
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Why troublesome and risky scale- up, if you can produce 500 grams and 1 ton with the same parameters on the same machine? |
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Why several cleanrooms, corridors and intermediate storage, if all your production can be done in one machine, one room, without intermediate storage? |
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Why waste energy if you can reduce the energy cost per tablet by 50%? |
ConsiGma™ offers you: (Based on customers analysis)
- Maximal end product safety by online quality control
- 10 times faster testing in R&D
- 40% saving on labour
- Reduction of manufacturing space by 60% compared to the current manufacturing space
- 50% energy savings based on reduced installed power and heat recovery
- From 0,5 to 5% yield improvement
ConsiGma™ has been successfully tested with more than 100 different formulations in our competence center in Antwerp and implemented in many ethical and generic research and manufacturing environments all over the world.
ConsiGma™ : tablet production targeting 6 sigma!
ConsiGma™ - oral solid dosage tableting line is designed for 'plug flow', first-in first-out, avoiding back mixing, providing a consistent quality and allowing for control of critical quality attributes in-line.
GEA Pharma Systems have also developed a blender which can be used for premixing or mixing the external phase in to the granules in a continuous way. GEA Pharma Systems - Courtoy™ developed advanced in-line PAT on their tablet presses which allows us now to provide a full tableting production line of solid dosage forms.
- Flexible batch size from 500g to many tonnes ... contact us for trials opportunities.
- Over 100 formulations already tested.
- No process scale-up as time is the only relevant factor in a continuous process
- Dramatically reduce development time and costs
- The system is compact (1/3 of a classic granulation line)
- Modular construction - fits perfectly into any R&D department or existing Solid Dosage suite (inclusive of a tablet press)
- Quality by Design (QbD) philosophy
Typical Applications - When should you think of Consigma?
- producing small batches of high added value products
- looking for the production/launch of new molecules
- reformulations and current non robust processes
- current formulations with specific granulation and/or drying issues
- site changes or production increase
- looking for a more econmic & greener way of production