GEA Pharma Systems integrate process engineering and PAT to provide Process Intelligence


The FDA’s PAT (process analytical technology) initiative has enabled GEA Pharma Systems to combine its equipment design skills and process engineering know-how in order to integrate online (PAT) analysers into its process systems in a way which can provide real insight into the operation of the process and help customers achieve key product quality target.

PAT for High Shear Granulation, Fluid Bed Processing and Single Pot Processing

Optical monitoring with the Lighthouse Probe™ technology
GEA Pharma Systems has joined forces with J&M Analytik AG to create a compact and cleanable in-process optical probe for use in powder processing equipment. The probe overcomes the traditional problem of observation windows fouling during processing.

The result is the novel Lighthouse Probe™, which can be used with a range of spectroscopic
techniques, including NIR and UV/vis, to overcome the traditional problem of product sticking to observation windows ... Read more and download

Manual operated - Lighthouse Probe™ Technology
A compact and cleanable in-process manually operated optical probe for use in powder processing.
Spectral Range: 0.2 to 2,5μm (4000cm-1 to 50000cm-1) ... Read more and download

Automated - Lighthouse Probe™ Technology
A compact and cleanable in-process automated optical probe for use in powder processing.
Spectral Range: 0.2 to 2,5μm (4000cm-1 to 50000cm-1) ... Read more and download 

Fully Automated Process-Interface - Lighthouse Probe™ Technology
The Lighthouse Probe™ PAT tool can be used for real-time monitoring of chemical and pharmaceutical processes and provides inprocess window cleaning at any time, recalibration during the process, full CIP (cleaning) of wash housing and seal, and a clear view inside – even in difficult conditions ... Read more and download

PAT for Freeze Drying

TLC® - Thermodynamic Lyophilization Control 
A process analysing, monitoring and control tool for Freeze Drying in R+D applications and for full-scale production. GEA Lyophil has developed TLC as an in-line, non-invasive method of; monitoring the primary (main) drying, determining the end of the main drying, monitoring the secondary drying and determining the end of the secondary drying ... Read more and download