GEA Pharma Systems provides proven solutions for the most challenging dosage forms such as oncology drugs, MUPS tablets, effervescents or multi-layer pellets.
Oncology drugs require the highest level on containment. This is assured seamlessly by GEA Pharma Systems (GPS) material handling based on IBC technology in combination with the unbeaten MC split butterfly valve technology. While of course GPS provides containment for all granulation processes (integrated line, fluid bed granulation, single-pot) the unique MODUL™ technology offers an unbeaten solution for compression. All of this makes a worldwide accepted state-of-the-art solution while assuring optimal operator protection and minimising the risk of cross contamination.
Multi-Layer pellets are of increasing interest for dosage forms. With the GEA Pharma Systems FlexStream™ fluid bed coating technology, 1:10 weight gains without any need of batch splitting are possible. At the same time the technology offers a linear scale up, and the opportunity to inspect or even clean nozzles without the need to interrupt the process.
MUPS tablets are another modern dosage forms. Their preparation demands very high coating efficacy, which is perfectly provided by GEA Pharma Systems FlexStream™ technology, and the compression of MUPS tablets implies special challenges. The Courtoy™ tablet compression technology assures that independent of the tablet weight each tablet is compressed by the same compression force. The unique feeding system also minimises the risk of demixing the feed material.
Effervescent granules and tablets are a popular dosage form for many active ingredients. The production of these products requires special attention because of the influence of humidity on the stability of the product. The combined technologies of GEA Pharma Systems ensure a controlled production of these dosage forms from start to finish. With the UltimaPro™-FZ single pot processor, GEA Pharma Systems has the ideal solution for producing effervescent
granules, even using water as granulation liquid. Combined with the materials handling systems and the Courtoy™ tablet press, a complete production line, specifically designed for effervescent production can be delivered ... more information about effervescent production.
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