When dealing with highly potent substances, compression is probably the most challenging stage of the tablet manufacturing process. The main reasons are:

  • The complex mechanical design and construction of the inside of a tablet press.
  • The continuous flow of materials into and out of the press.
  • The need to clean a very complex system in case of product change-over, including upstream and downstream equipment.
  • The multiple interfaces between the tablet press and its environment (air inlet, tablet outlet, powder inlet, dust extraction), each requiring a contained interconnection.
  • The need for frequent tablet sampling for IPC – either manually or automatically.
<--- CLICK TO DOWNLOAD