The pilot scale top-drive High Shear Granulators are suitable
for granulation of pharmaceutical clinical batches and small scale
production batches (10 to 50 kg).
Unique process design
The key to success is the unique design of vessel and mixing
tools. The angled position of the mixing blades combined with the rounded edges
at the bottom of the vessel guarantee the typical rope-type movement for
optimal flow of product during granulation.
Several binder liquid spray systems are available to suit your process. Bowl
and mixing blades are shaped and mounted to minimize clearance for maximum
yield, without locally overheating the product.
During a discharge cycle, the centrifugal force created by the rotation of
the mixing arm will push the product in a natural way to a proportionally
regulated outlet valve at the side without compacting the wet granules. This
way we can accurately dose the finished granules to a calibration unit,
connected to the outlet.
Through-the-wall configuration
- Through-the- wall offers the best option in terms of cleanliness,
maintenance and explosion protection.
- The through-the wall configuration provides a sealed separation between
technical and GMP space by the machine itself
- This offers a clear containment concept including explosion area separation
that fulfills the latest requirements like ATEX.
- By keeping technical components out of the process room, the equipment is
much easier to clean.
- Maintenance is carried out from the technical area, reducing the need for
the maintenance engineer to work in a GMP area.
- This also reduces downtime and the risk of contamination. For ATEX, the
design allows the technical area to be classified as safe.
Contact:
GEA Pharma Systems AG
GPS Technology
Centre
PO Box 112, Hauptstrasse 145
CH-4416, Bubendorf,
Switzerland
Tel: +41 61 936 37 00 Fax: +41 61 936 37 30
tc@geapharmasystems.com