To meet the high requirements from the pharmaceutical industry, GEA Pharma
Systems has developed a series of spray dryers, the PHARMASD™ (PSD).
Pharmaceutical Spray Dryers
The main advantage to
powder producers is the ability to control powder form. Niro spray dryers are
designed to produce the desired properties: particle size, bulk density,
moisture content, solubility, dispersibility etc. Product application: All
pumpable products whether heat or non-heat sensitive.
PHARMASD™ (Pharma
Spray Dryers) sizes: 1, 2, 3, 4, 5, 6 and 7.
Capacity ranges: from 80
kg/h to 4000 kg/h drying process gas.
Tailor-made standards
The philosophy behind the design
is that a combination of standardised modules are built together to meet the
requirement of a specific task. Therefore, dryers of equal capacity may be
completely different with respect to design, configuration and physical
size.
Plant components for customised solutions
Single-unit
manufacturing combined with the use of standard modules has replaced serial
plants production within the pharmaceutical industry, enabling truly customized
solutions based on proven systems. Each module, indeed each system and plant
component, must observe strict requirements and regulatory standards around the
world.
PHARMASD™ Design Options:
- Equipment for closed cycle operation
- Facilities for hot gas sanitisation
- Specially designed pharmaceutical flanges for duct connections
- Construction materials meeting FDA requirements
- HEPA filters for gas streams
- Special air disperser design
- Swirl cone for chamber access - no chamber door with risk for contamination
- CIP equipment
- Mirror polished surface
- Explosion protection systems
Spray Drying organic solvents
The use of organic
solvents when preparing pharmaceutical ingredients poses a challenge in the
drying process, which has resulted in the use of nitrogen as a drying gas and
closed cycle operation. Our spray dryers can be configured for drying of
compounds that are based on acetone, methylene chloride, ethanol, and other
organic solvents. The drying parameters and capacity vary greatly, depending on
the solvent used, as shown in the tables below.