Consigma™ - Continuous oral solid dosage tablet manufacturing is designed for 'plug flow', first-in first-out, avoiding back mixing, providing a consistent quality and allowing for control of critical quality attributes in-line.

Flexible batch size from 500g too many tonnes ... contact us for trials opportunities.

A movie, the drivers for selecting this continuous system and some examples of implementation can be found on www.consigma.be

Continuous Tablet Manufacturing allows the pharmaceutical industry to bring products to the market faster, in a more flexible and environmentally conscious way.  

  • No process scale-up as time is the only relevant factor in a continuous process
  • Dramatically reduce development time and costs
  • The system is compact (1/3 of a classic granulation line)
  • Modular construction - fits perfectly into any R&D department or existing Solid Dosage suite (inclusive of a tablet press)
  • Quality by Design (QbD) philosophy

Manufacture all your products with maximum flexibility at affordable costs

No more products in quarantine, no more sampling, no more rejects, no more scale-up, Just-In-Time production : COST REDUCTION.

  • Continuous high shear granulation and drying leads the way to a risk based approach and lean manufacturing.
  • Process know-how and control on a micro-scale results in guaranteed quality, avoiding end of line testing and allowing for parametric product release.
  • Full flexibility in batch size (simply by adjusting the time of production) enables you to produce your products to meet demand, producing exactly the quantity you need, while keeping your expensive clean room space reduced to a minimum.

Ensure a bright and healthy future for our children and increase your profitability

Consigma™ drastically reduces time to market of new medicines.

  • The operating principle of Consigma™ allows you to explore the design space of the process within days instead of weeks, thereby reducing development time and cost significantly.
  • The same machine can manufacture your development, pilot, clinical and production batches, simply by running for a longer time. This avoids lengthy and costly validation and process scale-up efforts, helping to bring your products to the market much faster.

Power your business while considering our planet

A small machine delivering maximum output with minimal utilities in a continuous way.

  • No peak consumptions, reduced space requirement, smaller buildings, smaller clean rooms. All these advantages lead to less consumption of the precious resources of our earth.
  • Consigma™ is also equipped with an advanced process control system resulting in guaranteed quality results and avoiding the generation of toxic waste.
  • Finally, the machine is contained to protect the operator and environment and prepared for production of molecules for decades to come.
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