Freeze Drying Production Systems
Automation and highest contamination prevention
There
is an increasing trend towards greater process automation to ensure product
consistency and the safety of operators when handling toxic materials. GEA
Lyophil’s LYOVAC® production systems provide the highest level of
automation by integrating Freeze Dryers, Automatic Loading and Unloading
Systems, Isolators and other components while enabling Process Analytical
Technology (PAT) to be used to monitor production throughout the process.
A typical Freeze Dryer Production System incorporates the
following components:
- Multiple Freeze Dryers
- Automatic Loading and Unloading System (ALUS®)
- Common CIP-Skid
- Isolator or RABs
- SCADA System
Every system is designed to allow high productivity while maintaining total
control over the process. These systems also give priority to the issues of
product integrity and operator protection and come with built-in CIP/SIP
systems and in-line quality control through PAT.
Integration Skills
Various production systems
incorporating ALUS, RABS or isolators and CIP-Skids of different suppliers with
their Lyovac ® Freeze Dryers have proven GEA Lyophil’s integration skills and
ability for successful managing projects with different partners.
System Configurations
GEA Lyophil production systems
fulfill the requirements of the pharmaceutical industry for reliable, validated
production. GEA Lyophil can deliver both standard and customized plant
configurations and make sure that individual process requirements are met.
Depending on the customers’ space and installation requirements, the
production freeze dryer plant can be installed on one or two floors, as
pass-through units with loading and unloading on different sides of the freeze
dryer or with loading/unloading on the same side. There is a big variety of
configurations GEA Lyophil has designed and installed.