To meet the high requirements from the pharmaceutical industry, GEA Pharma Systems has developed a series of spray dryers, the PHARMASD™ (PSD).
Pharmaceutical Spray Dryers
The main advantage to powder producers is the ability to control powder form. Niro spray dryers are designed to produce the desired properties: particle size, bulk density, moisture content, solubility, dispersibility etc. Product application: All pumpable products whether heat or non-heat sensitive.
PHARMASD™ (Pharma Spray Dryers) sizes: 1, 2, 3, 4, 5, 6 and 7.
Capacity ranges: from 80 kg/h to 4000 kg/h drying process gas.
Tailor-made standards
The philosophy behind the design is that a combination of standardised modules are built together to meet the requirement of a specific task. Therefore, dryers of equal capacity may be completely different with respect to design, configuration and physical size.
Plant components for customised solutions
Single-unit manufacturing combined with the use of standard modules has replaced serial plants production within the pharmaceutical industry, enabling truly customized solutions based on proven systems. Each module, indeed each system and plant component, must observe strict requirements and regulatory standards around the world.
PHARMASD™ Design Options:
- Equipment for closed cycle operation
- Facilities for hot gas sanitisation
- Specially designed pharmaceutical flanges for duct connections
- Construction materials meeting FDA requirements
- HEPA filters for gas streams
- Special air disperser design
- Swirl cone for chamber access - no chamber door with risk for contamination
- CIP equipment
- Mirror polished surface
- Explosion protection systems
Spray Drying organic solvents
The use of organic solvents when preparing pharmaceutical ingredients poses a challenge in the drying process, which has resulted in the use of nitrogen as a drying gas and closed cycle operation. Our spray dryers can be configured for drying of compounds that are based on acetone, methylene chloride, ethanol, and other organic solvents. The drying parameters and capacity vary greatly, depending on the solvent used, as shown in the tables below.