GEA Niro has developed a new series of spray dryers dedicated to
the pharmaceutical manufacturing. The new dryers, named PHARMASD™ (PSD) have
been designed using standard modules that incorporate all the required features
necessary for cGMP production in the environment of a pharmaceutical plant.
The philosophy behind the design is that a combination of
standardised modules is built together to meet the requirement for a specific
duty. Therefore, dryers of equal capacity may be completely different with
respect to design, configuration and physical size. This allows Niro to focus
specifically on the needs of the customer and the demands of the process
without physical limitations to the design of the equipment.
Cyclone
insulated: Ø 710 mm for PSD-5
The PSD dryers either use hot air or
nitrogen as drying gas. Nitrogen is used when drying non-aqueous compounds. The
dryers can be designed for drying of a wide range of compounds that are based
on acetone, methylene chloride, ethanol, and other organic solvents. The drying
process and product characteristics vary greatly, depending on the solvent
used.
PHARMASD™ DESIGN OPTIONS
- Equipment for closed cycle operation
- Facilities for hot gas sanitisation
- Specially designed pharmaceutical flanges for duct connections
- Construction materials meeting FDA requirements
- HEPA filters for gas streams
- Special air disperser design
- Swirl cone for chamber access - no chamber door with risk for contamination
- CIP equipment
As with all Niro plant equipment, each system component meets the strictest
requirements and regulatory standards.
The PSD range of
pharmaceutical dryers extends from the PSD-1 with a nominal drying gas rate of
80kg/hr up to the PSD-7 with a nominal drying gas rate of 4,000 kg/hr.