IBC Charging Station
IBC Charging Station

IBC system key process flow interfaces for a granulation area 

The effective and safe transfer of both excipients and active ingredients is essential and there are a number of option:

Gravity feeding

Gravity loading through a discharge station from the level above or via the post hoist are ideal solutions ensuring containment and simplicity of cleaning. API discharge vessels can be used to discharge into the granulator for the more potent applications.

Vacuum feeding – Room Height Restrictions

Where room height constraints prevail, a contained Vacuum Station is an option incorporating containment valves which will limit airborne dust, and may therefore assist in reducing area classifications. It is also possible to improve safety by using the containment valve interlocking features with a nitrogen purge system.

Unloading of the granulation equipment

Can incorporate in-line sieving or milling before the granules are loaded into a container. Lubricant or other materials may then be added (using charge containers) and blended with the granules.

Typical Granulation suite layout
Typical Granulation suite layout