Fluid Bed Processors Granulator, Dryer, Pelletizer and Coater by Aeromatic-Fielder™

For fifty years, Aeromatic-Fielder™ has supplied fluid bed processors for blending, granulating, drying, pelletizing and coating to the pharmaceutical industry. This includes small capacity systems designed for R & D as well as industrial size plants for batch production of pharmaceutical compounds under cGMP conditions. Using proven standard components, Aeromatic-Fielder™ can supply both simplicity and flexibility in plant design. User selected process options, cleaning equipment, control systems and PAT technologies combine in a system to meet process requirements exactly. This approach ensures that qualification and validation procedures are kept to a minimum.

Processing Modules:

• Dryer – with very short process time
• Top Spray Granulator – granulation and drying
  in a single pot process
• Spray Dryer Granulator – with batch or continuous discharge
• Precision Granulator™ – 'novel' granulation process
• Precision Coater™ – high spray rates for short processes

Plant design:

• Through-the-wall configuration
• A range of solvent emission controls
• Inlet air preparation unit – Inlet air is treated using a series of filters and conditioning units according to the sensitivity of the process and the ambient climatic conditions
• A range of process filters that can be interchanged for more than one type of process.

Unique to Aeromatic-Fielder fluid beds:

• Non-Sifting Gill Plate™ air distributor technology – uses an innovative design and a directed airflow to offer excellent uniformity of air distribution, for improved processing and product discharge
• Inlet air plenum – a novel air inlet plenum improves performance and reduces equipment height
• Most advance CIP technology that can be integrated with up- downstream equipment – CIP system allows cleaning to take place without removal of the process filters

Process Control & Monitoring:

• A range of control systems for maximum level of flexibility and functionality for process visualisation, automation and data recording
• PAT Integration – Combining process monitoring using online analysers, together with solid process engineering principles and advanced process modelling techniques will
  enable processes to be actively controlled in order to compensate for minor input variations (eg. raw materials) so that the specifications for the final product will be closer to the ideal target

Containment:

• Complete contained processing, utilizing Buck® high containment technology
• Product sampling

Continuous Improvement for Safety:

• EC type approved for pressure shock resistant integrated systems

Process assistance from GPS Technology Centre:

• A complete range of R & D and product testing services
• Test and optimise existing processes
• Develop new procedures
• Perform pilot scale production of any aqueous or solvent based pharmaceutical product.
• Demonstration and training facilities

Aeromatic-Fielder fluid bed product range:

• Development: MP-Micro™, Strea-1™, MP-1™, batches 20g - 6kg
• Pilot Scale: batches 1-30kg
• Production Scale: batches 15-1200kg

Integration for optimum process efficiency

Our complete range of process equipment is designed with system integration in mind. A modular approach allows customers to select standard process modules to suit project
needs. Fluid bed dryers and coaters can be combined with top drive and bottom-drive high shear mixer-granulators, wet and dry milling facilities, product handling systems, binder and
coating preparation units, filtration units, all designed for fully integrated systems. Safety, containment, product flow and building requirements are in-built for full integration for optimum process efficiency.